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10983129 Method for the detection of cancer cells by localization of peptides in nucleus as compared to cytoplasm  
The human LIV21 protein as a diagnostic and prognostic marker for various cancers and neurodegenerative diseases is provided. Methods for diagnosing and/or prognosing cancer utilizing the LIV21...
10983127 Device for diagnosing colorectal cancer and method for providing colorectal cancer diagnosis information  
The present invention relates to a device of diagnosing a colorectal cancer and a method for providing colorectal cancer diagnosis information. A colorectal cancer diagnosing device according to...
10983126 System and method for analyzing tissue for the presence of cancer using bio-marker profiles  
A system and method for intra-operative sample analysis including acquiring a tissue sample, preparing the tissue sample for mass spectrometry imaging, conducting a mass spectrometry imaging...
10982285 Biomarkers for the identification of prostate cancer and methods of use  
The present disclosure provides biomarkers for the identification of prostate cancer and methods of use. The present disclosure also provide biomarkers that can be used for determining risk of...
10982284 Compositions and methods APC, CREB, and BAD pathways to assess and affect cancer  
Disclosed are compositions and methods for assessing the apoptosis and survival BAD phosphorylation pathway (BAD pathway); and/or (2) the cell cycle role of APC in cell cycle regulation pathway...
10982279 Cell-free DNA for assessing and/or treating cancer  
This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having...
10981904 1,3,4-thiadiazole compounds and their use in treating cancer  
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, where: Q can be 1,2,4-triazin-3-yl, pyridazin-3-yl, 6-methylpyridazin-3-yl, or 6-fluoropyridazin-3-yl; R1 can be hydrogen,...
10981892 Acyl sulfonamides that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer  
The aryl sulfonamide compounds of this invention have powerful and cell-type specific Bcl inhibitory activity. Selected compounds in this class promote apoptosis in senescent cells, and are being...
10980873 Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-deltaC virus) in cancer therapy  
The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been...
10980869 Fusion proteins comprising an anti-CD40 antibody and cancer antigens  
The present invention includes compositions and methods for the expression, secretion and use of novel compositions for use as, e.g., vaccines and antigen delivery vectors, to delivery antigens to...
10980826 Pharmaceutical composition for treating and/or preventing cancer  
The present application provides a pharmaceutical composition for treating and/or preventing a cancer comprising, as an active ingredient, a polynucleotide derived from miRNA associated with the...
10980821 Triphenylphosphonium-derivative compounds for eradicating cancer stem cells  
Tri-phenyl-phosphonium (TPP) is a non-toxic chemical moiety that functionally behaves as a mitochondrial targeting signaling in living cells. TPP-related compounds may be utilized to target...
10980806 Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer  
A compound, or a pharmaceutically acceptable salt or ester thereof, according to formula I: R20—(Z)b—(Y)c—(R21)a—(X)d—R22—R23 wherein R20 is aryl, substituted aryl, heteroaryl, substituted...
10980795 Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan  
Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the...
10980793 Methods of treating cancer with farnesyltransferase inhibitors  
The present invention relates to the field of cancer therapy. Specifically, provided are methods of treating cancer, for example, peripheral T-cell lymphoma (“PTCL”), with a farnesyltransferase...
10980765 Isothiocyanatostilbenes as a novel method and product for treating cancer  
Products and methods for treating cancer in a human patient comprising administering to the patient therapeutically effective amount of a first pharmaceutically active agent, wherein the first...
10976320 Methods for identifying and treating cancer patients  
Methods for identifying and treating cancer patients likely to respond to topoisomerase inhibitors or likely to fail to respond to topoisomerase inhibitors are provided. The methods take advantage...
10976319 Cell response assay for cancer and methods of producing and using same  
A cell response assay for cancer is provided. In the assay, the levels of a cancer cell type biomarker, a chemo resistance biomarker and a metastatic potential biomarker are simultaneously...
10976318 Method of treating cancer using a caspase-4 inhibitor  
The present invention relates to the use as a biomarker of the active form of a human caspase protein, preferably the human caspase-4 or caspase-1, or of the active form of the protein encoded by...
10975443 Detecting breast cancer  
Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.
10975442 Molecular biomarkers for cancer immunotherapy  
In one aspect, provided herein is a method comprising: (a) (i) determining cytolytic activity in a tumor from the subject; and/or (ii) determining genetic alterations associated with cytolytic...
10975431 Cell-free DNA for assessing and/or treating cancer  
This document relates to methods and materials for assessed, monitored, and/or treated mammals (e.g., humans) having cancer. For example, methods and materials for identifying a mammal as having...
10975374 Combination vectors and methods for treating cancer  
A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such...
10975163 Methods of increasing delivery of anti-cancer agents to targets  
The present invention provides compositions and methods for increasing the permeability of a stroma around a neoplasm, and particularly to cancer cells associated with solid tumors. In one...
10975146 Interleukin-1 inhibition for combination treatment of pancreatic cancer  
A composition for IL-1 inhibition in combination with cancer therapies (e.g., chemotherapeutics including chemotherapy protective drugs) is provided for use in treating pancreatic cancer cachexia...
10975067 Methods and compositions useful in treating cancer and reducing Wnt mediated effects in a cell  
Provided herein are novel compounds, pharmaceutical compositions for use, inter alia, in methods of reducing Wnt-mediated effects and treating cancer.
10974077 Low intensity focused ultrasound for treating cancer and metastasis  
Systems and methods for treating cancer and for preventing metastasis using low intensity focused ultrasound in combination with an anti-cancer therapy are disclosed.
10974059 Treatment of cancer or tumors induced by the release of heat generated by various chains of magnetosomes extracted from magnetotactic bacteria and submitted to an alternating magnetic field  
A method for the treatment of tumor(s) or tumor cell(s) or cancer(s) in a subject in need by the generation of heat. The latter is produced by chains of magnetosomes extracted from whole...
10973917 MRNA combination therapy for the treatment of cancer  
The present disclosure relates to the use of nucleic acid (e.g., mRNA) combination therapies for the treatment of cancer. The disclosure provides compositions, and methods for their preparation,...
10973894 Methods of isolating T cells having antigenic specificity for a cancer-specific mutation  
Disclosed are methods of isolating T cells having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation, the method comprising: identifying one or more...
10973893 Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer  
The present invention provides a universal, yet adaptable, anti-tag chimeric antigen receptor (AT-CAR) system which provides T cells with the ability and specificity to recognize and kill target...
10973884 Pharmaceutical composition for preventing and treating cancer, containing CYB5R3 gene or protein as active ingredient  
The present invention relates to a pharmaceutical composition for treating cancer, containing cytochrome b5 reductase 3 (CYB5R3) protein as an active ingredient. Over-expression of CYB5R3 in...
10973870 Methods of treating prostate cancer with GnRH antagonist  
The invention provides methods and dosing regimens for safely and effectively treating androgen-dependent prostate cancer with a gonadotrophin releasing hormone (GnRH) antagonist without causing a...
10973849 Rhenium complexes and methods of use for treating cancer  
A composition comprising the following structure: (formula I) wherein Re represents a rhenium ion having a +1 charge; (formula II) represents an uncharged bidentate bicyclic ligand bonded to the...
10973843 Method for monitoring cancer and for regulation of semaphorin 4D to improve cancer immunotherapy regimens  
The present invention provides a method of inhibiting tumor-mediated immunosuppression in a subject, comprising administering to the subject a therapeutically effective amount of an agent that...
10973823 Anti-cancer composition consisting of halofuginone and sesquiterpene lactone compounds of artemisia apiacea and use thereof  
Provided is a combined pharmaceutical composition of HF and an Artemisia annua sesquiterpene lactone compound for treating cancers. The active ingredients of the combined pharmaceutical...
10973799 Isoflavonoid compositions and methods for the treatment of cancer  
Provided herein is a pharmaceutical composition comprising an isoflavonoid derivative and a cyclodextrin. Also provided herein are methods of treating cancer, sensitizing cancer cells, and...
10973788 Treatment of cancer with specific RXR agonists  
A method of treating cancer is disclosed comprising administering to a patient in need of such treatment a RXR agonist at a level below the RAR activating threshold and at or above the RXR...
10973456 System for screening and diagnosis of skin cancer  
This invention provides a non-invasive diagnosis system that is not only capable of producing high-resolution, three-dimensional images of abnormalities of tissue growth inside the body but, it...
10973251 Nutritional treatment for cancer  
Methods of screening cancerous cells for nutritional weaknesses and methods of treating cancer nutritionally are disclosed. Certain cancers depend on being supplied with one or more nutrients that...
10971268 Method of providing information for the diagnosis of pancreatic cancer using Bayesian network based on artificial intelligence, computer program, and computer-readable recording media using the same  
The present invention provides a method of providing information necessary for diagnosing pancreatic cancer using an artificial intelligence-based Bayesian network, comprising: generating a...
10969392 Methods and systems for predicting response to immunotherapies for treatment of cancer  
A method of detecting cell membrane expression of an MHC molecule in a subject, a method of treating cancer in a subject with an immunotherapeutic agent, and an MHC complex are provided. The...
10969380 Simultaneous detection of cannibalism and senescence as prognostic marker for cancer  
The present inventors show that cannibal cells can undergo senescence after entosis in vivo and that the tumor suppressive protein p53 act as a repressor of this phenomenon. They therefore propose...
10968196 Substituted β-lapachones for treating cancer  
Compounds are provided that are useful in treating cancer and neurodegeneration. The compounds comprise a β-lapachone or β-lapachone derivative tricyclic ortho-naphthoguinone moiety linked to a...
10967077 Imaging of metastatic or recurrent cancer  
The present disclosure relates to methods of administering [18F]-FACBC. The present disclosure also relates to use of [18F]-FACBC in methods for imaging, diagnosing and monitoring metastasis or...
10967060 Synergistic combination of immunologic inhibitors for the treatment of cancer  
The present disclosure provides combinations of immunologic inhibitors for the treatment of cancer. In some embodiments, the methods involve the use of a combination of at least two of the...
10967054 Methods of cancer treatment using activated T cells  
Provided is a method of treating a cancer in an individual using activated T cells or PBMCs induced by antigen presenting cells (such as dendritic cells) loaded with a plurality of tumor antigen...
10966998 Cancer therapy via a combination of epigenetic modulation and immune modulation  
Cancer therapies that combine epigenetic modulating agent(s) with immune modulating agent(s), which were remarkably identified to provide an improved treatment regimen over single agent therapy,...
10966986 Compounds, compositions and methods for cancer patient stratification and cancer treatment  
The present invention features improved Compounds, especially (I) methods of identifying patients having Cancer using biomarkers (e.g., PDE3A, SLFN12 and/or CREB3L1) that correlate with drug...
10966957 Method of treating cancer with combinations of histone deacetylase inhibitors (HDAC1) substances  
A method for treating cancer is described using combination therapies comprising the use of hyperbaric oxygen with histone deacetylase inhibitors, with and without glycolytic therapies. The...

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